Kovina Therapeutics
Kovina Therapeutics Transforming HPV Care

Transforming
HPV Care

First-in-class small molecule antivirals to treat HPV cancers and premalignant infections

Kovina background illustration
About us
Shape V1 Image - Subscription X Webflow Template

Kovina Therapeutics is a preclinical stage biotechnology company developing targeted antiviral therapeutics designed to eliminate
Human Papillomavirus (HPV) driven cancers and premalignant infections caused by HPV.

01

HPV causes cancer

An estimated 630,000 HPV-related malignancies are diagnosed each year, representing 5% of the cancer burden worldwide.

Cells Icon
02

Most cervical and oral cancers are caused by HPV

HPV causes nearly all cervical and the majority of oropharyngeal cancers. Available treatments—surgery, radiation, chemotherapy, and immunotherapy—often come with significant side effects.

03

HPV vaccine does not treat existing HPV cancers or infections

The HPV vaccine prevents new infections but does not treat HPV induced cancers or the millions of existing HPV infections such as cervical and anal dysplasia that can progress to cancer.

Syringe icon
Our approach

Our unique antiviral specifically targets the HPV E6 oncogene

First-in-class small molecules
We are developing first-in-class small molecules that selectively kill HPV-infected cells by disabling HPV E6, the oncogenic driver expressed in both precancerous and cancerous tissue.
Apoptosis in
infected cells
By inactivating HPV-E6, our compounds trigger apoptosis in infected cells, sparing healthy tissue.
Treating the full spectrum of HPV disease
This approach enables treatment across the full spectrum of HPV disease — from premalignant infections to invasive cancers.
Lab technician testing for HPV

Our commitment to patients

Kovina is committed to providing patients infected with HPV novel treatment options not available in the market today.  For patients living with HPV, Kovina’s development efforts provide hope for a non-surgical option to treat cancers and premalignant infections caused by HPV.  

Our leadership
Our board of directors
Our scientific advisory board
Our investors

Investors and Partners

Backed by premier academic, institutional, and nonprofit partners: validating our science and strategic vision.

IU Ventures
Elevate Ventures
BioCrossroads
Luson Bioventures
Indiana Biosciences Research Institute
CDDDA
MBCCC
Indiana University
BrightEdge

Grantors

NCI
NIAID
NIDCR
In the press
Get in touch
Thank you! We’ll get back to you soon

We have received your message and will get back to you as soon as possible. Our team is dedicated to providing the best support and we appreciate your patience.

Oops! Something went wrong.